The Biological Problem of To-day: Preformation Or Epigenesis?
 The Basis of a Theory of Organic Development

by Oscar Hertwig

"The Biological Problem of To-day: Preformation Or Epigenesis?" by Oscar Hertwig is a scientific treatise written in the late 19th century. This work delves into the biological debate concerning the nature of development, specifically examining two opposing theories: preformation, which posits that all characteristics of an organism are already present in a miniature form within the germ, and epigenesis, which suggests that development is a progressive formation from an initially unorganized state. Hertwig's exploration of these theories is informed by his expertise in embryology and cell biology. The opening of the book sets up the central question regarding whether embryonic development represents a preformed structure or an elaborative process shaped by environmental influences. Hertwig introduces the ideas of other biologists, particularly focusing on August Weismann's germplasm theory, which classifies hereditary material as distinct and stable while addressing the complexities of reproduction and differentiation. Through critical analysis, Hertwig aims to establish that true development relies on epigenesis, where the organism grows and develops through interactions with its surroundings, rather than merely revealing what was predetermined in the germ. The opening serves as a prelude to a deeper examination of the implications each theory carries for understanding heredity and the intricacies of life.